When smoked, mullein has been said to help repair lung damage caused by tobacco. Tinctures and teas have been used to treat bronchitis, tuberculosis, dry cough, as well as hemorrhoids.
Poultices were used by the Zuni people to treat skin ailments and athlete’s foot. Tinctures have traditionally be used to treat a large variety of skin conditions.
The flowers contain concentrated bactericide and have anti-tumoral properties. The leaves contain several compounds that are toxic to fish, and have been used in fishing.
Parts of the plant have also been used to make dyes and candle wicks.